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KMID : 0602819950010010064
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Korean Journal of Bronchoesophagology
1995 Volume.1 No. 1 p.64 ~ p.68
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Morphologic Changes of Anchoring Fibers in Vocal Polyps
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Abstract
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Vocal folds injury from vocal abuse is important topics of phonosurgery. Recent
advances in diagnostic equipment, phonosurgery and speech analysis equipment have provided
a lot of information abut fine movement of the vocal folds. However, predicting the reaction
of the vocal folds to phonatory trauma remains difficult.
The vocal folds need to withstand great vibratory and shearing stress and anchoring fibers of
basement membrane zone play a role in maintaining structural integrity of histologically
different epidermis and superficial layer of lamina propria(cover of vocal folds).
The purpose of this study is to demonstrate the changes of anchoring fibers in vocal
polypusing transmission electron microscope. Various defects were observed: a irregular
thickening of basement membrane, a near absence of normal anchoring fiber, a lot of electron
dense material in superficial layer of lamina propria, a destruction of hemidesmosome and
many vesicles carrying electron dense material in basal keratinocyte.
These observations were suggestive of a hyperactivity of basal keratinocyte of vocal folds
epithelium in response to vibratory stress.
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